Krystal Biotech, Inc. KRYS

Healthcare SIC 2836 - Biological Products, (No Diagnostic Substances) NAICS Manufacturing › Chemical Manufacturing › Pharmaceutical and Medicine Manufacturing › Biological Product (except Diagnostic) Manufacturing derived Nasdaq

We are a fully integrated, global, commercial-stage biotechnology company focused on the discovery, development, manufacturing and commercialization of genetic medicines to treat diseases with high unmet medical needs. Using our patented gene therapy technology platform that is based on engineered herpes simplex virus-1 ("HSV-1"), we create vectors that efficiently deliver therapeutic transgenes to cells of interest in multiple organ systems. The cell's own machinery then transcribes and translates the transgene to treat the disease. Our vectors are amenable to formulation for non-invasive or minimally invasive routes of administration at a healthcare professional's office or in the patient's home by a healthcare professional, caregiver, or directly by the patient themselves. Our innovative technology platform is supported by two in-house, commercial scale Current Good Manufacturing Practice ("CGMP") manufacturing facilities.

Last close 311.50 2026-10-23
Market cap $9.22B 2026-06-30 share count
52-week range 183.26 - 382.54

Valuation FY2025 figures against the last close

P/S23.7x
P/E45.5x
P/FCF48.8x
EV/EBITDA55.2x
Dividend yield—
Diluted EPS6.84

Annual financial statements

Income statement

Fiscal year FY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Revenue $389.1M$290.5M$50.7M$0$0—————
R&D $58.0M$53.6M$46.4M$42.5M$27.9M$17.9M$15.6M$7.8M$3.2M$741.0K
SG&A $146.7M$113.6M$98.3M$77.7M$40.4M$15.1M$6.5M$4.2M$1.6M$402.0K
Total operating expenses $227.8M$224.8M$160.3M$145.2M$68.3M$33.0M$22.1M$11.9M$4.8M$1.1M
Operating income $161.3M$65.7M-$109.6M-$145.2M-$68.3M-$33.0M-$22.1M-$11.9M-$4.8M-$1.1M
Interest expense ——$0$0$1.5M$0————
Pre-tax income $189.5M$95.4M$12.9M-$140.0M-$69.6M-$32.2M-$19.1M-$10.9M-$7.9M—
Income tax $15.4M$6.2M$2.0M$0$0$0$0$0$0—
Net income $204.8M$89.2M$10.9M-$140.0M-$69.6M-$32.2M-$19.1M-$10.9M-$7.9M-$1.1M
EPS, basic 7.083.120.40-5.49-3.13-1.71————
EPS, diluted 6.843.000.39-5.49-3.13-1.71-1.20-0.97-1.48-1.31
Shares, diluted (wtd. avg.) 30.0M29.7M27.8M25.5M22.2M18.8M————

Balance sheet

Fiscal year FY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Cash and equivalents $496.3M$344.9M$358.3M$161.9M$341.2M$268.3M$187.5M$103.7M$49.6M$1.9M
Short-term investments $331.5M$252.7M$173.8M$217.3M$96.8M$3.0M$6.2M$8.1M——
Receivables $127.4M$104.7M$42.0M$0——————
Inventory $40.5M$26.5M$7.0M$0——————
Total current assets $1.02B$742.0M$587.9M$383.8M$442.3M$275.1M$195.9M$112.7M$49.9M$2.2M
Property, plant and equipment $150.8M$155.2M$161.2M$161.7M$112.4M$30.9M$8.5M$3.0M$200.0K$13.0K
Total assets $1.33B$1.06B$818.4M$558.5M$626.3M$310.8M$209.0M$116.1M$50.1M$2.2M
Accounts payable $3.2M$5.0M$4.1M$4.0M$8.4M$2.1M$1.0M$888.0K$193.0K$42.0K
Total current liabilities $102.9M$102.0M$33.1M$28.8M$25.7M$15.5M$3.3M$2.6M$640.0K$43.0K
Long-term debt ————————$4.3M—
Total liabilities $114.2M$109.5M$39.7M$36.2M$32.7M$18.8M$6.1M$2.9M$640.0K$1.9M
Retained earnings $24.2M-$180.7M-$269.8M-$280.8M-$140.8M-$71.2M-$39.0M-$20.0M-$9.1M-$1.1M
Total equity $1.22B$946.4M$778.6M$522.2M$593.6M$292.1M$202.9M$113.2M$49.5M$289.0K

Cash flow

Fiscal year FY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018FY2017FY2016
Operating cash flow $200.9M$123.4M-$88.8M-$100.6M-$47.9M-$26.1M-$18.7M-$9.4M-$3.9M-$1.3M
Depreciation and amortisation $5.7M$6.0M$5.0M$2.6M$1.8M$1.9M$1.1M$141.0K$23.0K$2.0K
Stock-based compensation $54.5M$49.1M$39.9M$33.2M$15.3M$3.3M$1.2M$792.0K$246.0K$33.0K
Capital expenditure $12.0M$4.2M$11.8M$53.0M$68.3M$14.8M$6.4M$2.2M$210.0K$15.0K
Investing cash flow -$58.4M-$163.4M$82.6M-$114.1M-$226.8M-$11.2M-$5.0M-$10.3M-$210.0K-$15.0K
Financing cash flow $8.7M$27.0M$202.8M$35.3M$347.7M$118.0M$107.5M$73.8M$51.8M$3.2M

Figures as tagged in each year's own filing, in US dollars. A year restated by a later filing shows the restated figure. Capital expenditure, dividends and buybacks are cash out, shown positive. A line the filer does not report is not listed. Latest from accession 0001711279-26-000016.

Plot the figures US dollars

Income statement Revenue Cost of revenue Gross profit R&D SG&A Total operating expenses Operating income Interest expense Pre-tax income Income tax Net income EPS, basic EPS, diluted Shares, diluted (wtd. avg.)
Balance sheet Cash and equivalents Short-term investments Receivables Inventory Total current assets Property, plant and equipment Goodwill Other intangibles Total assets Accounts payable Short-term debt Total current liabilities Long-term debt Total liabilities Retained earnings Total equity
Cash flow Operating cash flow Depreciation and amortisation Stock-based compensation Capital expenditure Investing cash flow Financing cash flow Dividends paid Buybacks
  • Revenue
  • Gross profit
  • Net income
Revenue, Gross profit, Net income by fiscal year, in US dollars The same figures are in the table below this chart. -200M 0 200M 400M Net income, FY2016: -1.1M Net income, FY2017: -7.9M Net income, FY2018: -10.9M Net income, FY2019: -19.1M Net income, FY2020: -32.2M Revenue, FY2021: 0 Net income, FY2021: -69.6M Revenue, FY2022: 0 Net income, FY2022: -140M Revenue, FY2023: 50.7M Net income, FY2023: 10.9M Revenue, FY2024: 290.5M Net income, FY2024: 89.2M Revenue, FY2025: 389.1M Net income, FY2025: 204.8M FY2016 FY2017 FY2018 FY2019 FY2020 FY2021 FY2022 FY2023 FY2024 FY2025
Fiscal year FY2016FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025
Revenue — — — — — $0 $0 $50.7M $290.5M $389.1M
Gross profit — — — — — — — — — —
Net income -$1.1M -$7.9M -$10.9M -$19.1M -$32.2M -$69.6M -$140.0M $10.9M $89.2M $204.8M

Recent filings and events

  • Results announced The quarterly or annual earnings release. Arrives four times a year from almost every company here. Item 2.02
  • Other event The catch-all. The company chose to disclose something that fits no other item, so the content is whatever it says it is. Item 8.01
  • Shareholder vote The results of the annual meeting or a special vote. Item 5.07
  • Annual report filed A new 10-K. The figures and the business description on this site come from it. Form 10-K
  • Results announced Item 2.02
  • Results announced Item 2.02
  • Regulation FD disclosure Something the company told the market and had to tell everyone at once - usually a slide deck or a press release. Item 7.01
  • Regulation FD disclosure Item 7.01
  • Officer or director change Someone at the top arrived or left. The item covers everything from a board retirement to a chief executive being removed, and only the filing itself says which. Item 5.02
  • Results announced Item 2.02
  • Other event Item 8.01
  • Results announced Item 2.02

Item numbers are Form 8-K's own, and a filing date is up to four business days after the thing it reports. The same feed across the whole market.

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