Sagimet Biosciences Inc. SGMT
We are a clinical-stage biopharmaceutical company developing novel therapeutics called fatty acid synthase (FASN) inhibitors that target dysfunctional metabolic and fibrotic pathways in diseases resulting from the overproduction of the fatty acid, palmitate. Our lead drug candidate, denifanstat, is an oral, once-daily pill and selective FASN inhibitor in development for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), acne and select forms of cancer. Our second FASN inhibitor, TVB-3567, is a potent and selective small molecule FASN inhibitor in development for acne.
The critical role of FASN overactivity in MASH makes it an attractive target for drug therapy. Our FASN inhibitor, denifanstat, targets multiple drivers of MASH by reducing steatosis, inflammation and fibrosis.
Valuation FY2025 figures against the last close
Annual financial statements
Income statement
| Fiscal year | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Revenue | — | — | $2.0M | — | — |
| R&D | $39.1M | $38.4M | $19.8M | $24.9M | — |
| SG&A | $17.8M | $16.0M | $13.0M | $6.1M | — |
| Total operating expenses | $56.9M | $54.5M | $32.7M | $31.1M | — |
| Operating income | -$56.9M | -$54.5M | -$30.7M | -$31.1M | — |
| Pre-tax income | -$51.0M | -$45.6M | — | — | — |
| Income tax | $0 | $0 | — | — | — |
| Net income | -$51.0M | -$45.6M | -$27.9M | -$30.5M | — |
| EPS, basic | -1.58 | -1.45 | -2.66 | -165.20 | — |
| EPS, diluted | -1.58 | -1.45 | -2.66 | -165.20 | — |
| Shares, diluted (wtd. avg.) | 32.3M | 31.4M | 10.5M | 184,619 | — |
Balance sheet
| Fiscal year | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Cash and equivalents | $35.0M | $75.8M | $75.1M | $158.0K | $56.7M |
| Short-term investments | $78.1M | $75.4M | $19.8M | $32.2M | — |
| Total current assets | $116.4M | $152.8M | $96.6M | $32.8M | — |
| Total assets | $116.5M | $160.3M | $96.7M | $33.0M | — |
| Accounts payable | $1.3M | $1.4M | $186.0K | $1.1M | — |
| Total current liabilities | $5.1M | $4.5M | $5.7M | $5.3M | — |
| Total liabilities | — | — | $5.7M | $5.4M | — |
| Retained earnings | -$346.3M | -$295.3M | -$249.7M | -$221.9M | — |
| Total equity | $111.4M | $155.8M | $91.1M | -$186.9M | -$158.3M |
Cash flow
| Fiscal year | FY2025 | FY2024 | FY2023 | FY2022 | FY2021 |
|---|---|---|---|---|---|
| Operating cash flow | -$45.6M | -$42.4M | -$23.8M | -$24.5M | — |
| Stock-based compensation | $6.4M | $5.3M | $5.0M | $1.9M | — |
| Investing cash flow | $4.6M | -$61.7M | $12.6M | -$32.0M | — |
| Financing cash flow | $275.0K | $104.8M | $86.2M | -$73.0K | — |
Figures as tagged in each year's own filing, in US dollars. A year restated by a later filing shows the restated figure. Capital expenditure, dividends and buybacks are cash out, shown positive. A line the filer does not report is not listed. Latest from accession 0001104659-26-026140.
Plot the figures US dollars
- Revenue
- Gross profit
- Net income
| Fiscal year | FY2021 | FY2022 | FY2023 | FY2024 | FY2025 |
|---|---|---|---|---|---|
| Revenue | — | — | $2.0M | — | — |
| Gross profit | — | — | — | — | — |
| Net income | — | -$30.5M | -$27.9M | -$45.6M | -$51.0M |
Recent filings and events
- Other event The catch-all. The company chose to disclose something that fits no other item, so the content is whatever it says it is. Item 8.01
- Results announced The quarterly or annual earnings release. Arrives four times a year from almost every company here. Item 2.02
- Regulation FD disclosure Something the company told the market and had to tell everyone at once - usually a slide deck or a press release. Item 7.01
- Regulation FD disclosure Item 7.01
- Officer or director change Someone at the top arrived or left. The item covers everything from a board retirement to a chief executive being removed, and only the filing itself says which. Item 5.02
- Shareholder vote The results of the annual meeting or a special vote. Item 5.07
- Officer or director change Item 5.02
- Results announced Item 2.02
- Material agreement signed The company entered an agreement outside the ordinary course of business - a large contract, a credit facility, a merger agreement. Item 1.01
- Results announced Item 2.02
- Regulation FD disclosure Item 7.01
- Regulation FD disclosure Item 7.01
Item numbers are Form 8-K's own, and a filing date is up to four business days after the thing it reports. The same feed across the whole market.
Others in SIC 2834
| Ticker | Company | Market cap | P/E | Revenue growth |
|---|---|---|---|---|
| LLY | ELI LILLY & Co | $1.20T | 55.5x | 44.7% |
| JNJ | JOHNSON & JOHNSON | $635.76B | 23.9x | 6.0% |
| ABBV | AbbVie Inc. | $504.76B | 121.0x | 8.6% |
| MRK | Merck & Co., Inc. | $358.41B | 20.0x | 1.3% |
| ABT | ABBOTT LABORATORIES | $180.63B | 27.9x | 5.7% |
| PFE | PFIZER INC | $171.16B | 22.1x | -1.6% |
| VRTX | VERTEX PHARMACEUTICALS INC / MA | $132.80B | 34.2x | 8.9% |
| BMY | BRISTOL MYERS SQUIBB CO | $125.59B | 17.8x | -0.2% |